DiminishedConcern's photo
Wed 08/26/20 04:50 PM
Money be reasonably attractive and act like a simp

DiminishedConcern's photo
Wed 01/10/18 12:29 AM
I have always looked at time as a construct simply a man made system of measurement. Based on cyclical events and molecular half life. Physics and mathematics use it as a constant for equations. But is it truly a component of matter. Given environmental changes cyclical cycles and molecular half life can be altered. So if conditions changed which affected the predictable usage of "time" then would it just be readjusted to become useful again. Thinking along the lines of whatever greater system that might make something a constant like our gravity time ect. might not necessarily be consistent or present elsewhere in the universe at least not as we ascertain it here.

DiminishedConcern's photo
Wed 01/10/18 12:01 AM
I guess the real question is what is space itself. If it affects matter and antimatter then is it simply something that isn't there an absence or is it a constant force itself. Perhaps a differential pressure system in which suggests the opposite must exist elsewhere in greater amount.

DiminishedConcern's photo
Tue 01/09/18 11:42 PM
I added replies indicated by a hyphen to your questions posed.

Reverse aging?
To reverse aging all cells would need to be rebuilt and the DNA that is in new cells would need to be rebuilt constantly.
The problem I see is at what point and veracity should the process be interrupted? - I would say once a particular cellular line percentage loses a certain efficiency amount to perform it's function -

Menopause/maxipause?
Puberty?
Birth?
Conception?
- Thalamus and pituitary based hormones generally regulate progesterone testosterone estrogen and hgh to igf1. Dependence promoters can be altered.

The way I understand aging is that cellular generation is constructive until puberty. After puberty cellular generation is extirpating due to the degeneration of the DNA.

- Stem cells are active throughout one's lifetime there are areas known as niches from which propagation issues forth in each separate somatic line. Dna degradation generally isn't the conducive issue simply because dna repair mechanisms are generally very effective. So much so that after a gene edit it's discernable exactly how it will repair itself and is left to do so. More importantly is the gene expression values. Inconsistency and over or under expression can affect other gene dependent expression values. Causing a cascade shift register effect of pathways and causing other pliant genes to attempt to balance signalling errors. This is why everything is mirrored as a double stranded biological check sum -

If a process were invented to rebuild all DNA, is there a point of health that could be set? If so, could that point be maintained? - Absolutely and as processes improve the overall ease of doing so would inevitably increase -

http://e-drexler.com/d/06/00/EOC/EOC_Chapter_7.html#section08of08

Without completely rebuilding a body as a whole, the parts that were not rebuilt will affect those that were. Its a simple case of cause and effect.
Like someone with a bionic arm, trying to support the weight of a car, will break their back. - Organ transplantation is a prime example of singular systemic replacement. And soon there will be even less drawbacks if it's based from your own genomic data -

A common theme in science fiction depicts immortality losing the ability to reproduce. If an organism is immortal, there is no need to reproduce.
What other things might be nullified by reversing the aging process?
- None foreseeable we still have to exist within certain boundaries. Germlines wouldn't necessarily be affected by any typical gene edit nor would they be passed along to offspring. Leaving unadulterated reproduction probable given physiological ability is maintained unless they were selectively targeted to do otherwise -

Intellect (brain capacity)
Memory (synaptic function)
Immunity (mutability)
Energy Levels (calorie burning)

The complexity of a living body is interdependent on its mechanisms. Change one part, it affects all parts in some way.
- I would say the body seeks homeostasis but is adaptive or resistant reactive to stimulus especially on a cellular and genomic level -

DiminishedConcern's photo
Tue 11/07/17 02:20 AM
Telomeres are like error buffers they activate after rna transcription when mitochondrial replication completes. Resolving cross linking mutations and broken or cleaved dimers by zinc patching or signalling for apoptosis. This however doesn't avoid the damage or inherent mutations from occurring otherwise. Leaving consumer products such as pa65 relatively helpful but useless. By reverting progenitor cells such as basal skin cells to pluripotent form. One can then essentially reset the genetic format to inclinate conditions. And by using specific genes packaged to create that pluripotent condition and encapsulated into lentiviral vectors. One can effectively affluence any somatic cell line. The real trick is dosing or leaving enough cellular structure functioning to facilitate the change without systemic failure. Meaning if you have enough clout knowledge and coin we can inextricably reverse aging.

DiminishedConcern's photo
Sat 11/04/17 02:57 AM
Your genome is altered on a daily basis over 150k mutations occur in a person's lifespan. In contrast to your entire genome this is a paltry 2% at best and mostly erroneous and non beneficial. Viruses evolve at a much higher rate and won't stop simply due to anyone's morality. In fact they are so efficient we currently use them to alter genes. Genetic manipulation is simply taking control measures of adaptation these otherwise lengthy processes are shortened into a beneficial timeframe.